Hypothyroidism in a Case of Down Syndrome: A Case Report Hypothyroidism in Downs Syndrome

Abstract

A 28-day-old male neonate with Down Syndrome presented with persistent jaundice and was admitted to the NICU. In this case characteristic physical features of Down syndrome were present. Karyotyping confirmed the diagnosis of Downs syndrome. Further investigations included ultrasonography of the thyroid gland, which showed a reduced gland size, suggestive of thyroid dysgenesis. Abnormal thyroid function tests led to the diagnosis of hypothyroidism. Management with levothyroxine was started in appropriate doses. This report highlights the prevalence and implications of thyroid dysfunction in neonates with Down syndrome and underscores the importance of vigilant screening and comprehensive management to improve outcomes in this population.