Hypertension Secondary to 17 Alpha-Hydroxylase Deficiency in a Young Male: A Case Report

Abstract

This case report describes a 19-year-old male who initially presented with altered sensorium. The patient, without a relevant medical or family history, was first treated for hypokalemia, which resolved with potassium supplementation. Subsequent cardiology evaluation revealed persistent hypertension with blood pressures peaking at 170/110 mm Hg. Further investigations confirmed 17 alpha-hydroxylase deficiency, a rare cause of secondary hypertension associated with mineralocorticoid deficiency. This case underscores the importance of considering rare endocrinological disorders in young patients presenting with hypertension and electrolyte imbalances. Management strategies, diagnostic challenges, and outcomes are discussed, emphasizing the need for a thorough endocrinological assessment in similar presentations.