Amiodarone-Induced Hypothyroidism: A Case Report

Abstract

Amiodarone is an effective antiarrhythmic medication used for the treatment of various cardiac arrhythmias, but its use is associated with thyroid dysfunction, particularly hypothyroidism. This case report discusses a 61-year-old male who developed hypothyroidism following prolonged amiodarone therapy for ventricular arrhythmia. The patient presented with symptoms of fatigue, weight gain, and cold intolerance, and was found to have elevated TSH and low free T4 levels. He was managed with levothyroxine while continuing amiodarone therapy due to its necessity for arrhythmia control. Regular thyroid function monitoring was crucial in managing his condition effectively. The case highlights the need for awareness and regular screening for thyroid dysfunction in patients on long-term amiodarone therapy. Similar cases in the literature emphasize the variable incidence of amiodarone-induced hypothyroidism, particularly in iodine-sufficient regions. Early detection and appropriate management can prevent complications and improve patient outcomes.